Scientist converts skin cells into brain cells
Washington, July 29: A novel way of converting human skin cells directly into functional brain cells is likely to revolutionise regenerative medicine and drug discovery.
Sheng Ding's latest research from Gladstone Institutes offers new hope for tackling degenerative diseases like Alzheimer's, as well as for the possibility of cell-replacement therapy to reduce the trauma of millions of people affected by these irreversible conditions.
Ding, professor of pharmaceutical chemistry at the University of California-Los Angeles, used two genes and a microRNA to convert a skin sample from a 55-year-old woman directly into brain cells. MicroRNAs are tiny strands of genetic material that regulate almost every process in our cells.
Ding's research extends Gladstone scientist Shinya Yamanaka's work who offered a method for avoiding the embryonic stem cells and creating an entirely new platform for fundamental studies of human disease, reports the journal Cell Stem Cell.
Use of embryonic stem cells is controversial, which is why Yamanaka's discovery of an alternate way to obtain human stem cells is so important, according to a Gladstone statement.
"This technology should allow us to very rapidly model neurodegenerative diseases in a dish by making nerve cells from individual patients in just a matter of days rather than the months required previously," said Stuart Lipton, who collaborated with Ding in the study.
Lipton directs the Del E. Webb Neuroscience, Aging and Stem Cell Research Center at Sanford-Burnham Medical Research Institute. IANS
Lastupdate on : Fri, 29 Jul 2011 21:30:00 Makkah time
Lastupdate on : Fri, 29 Jul 2011 18:30:00 GMT
Lastupdate on : Sat, 30 Jul 2011 00:00:00 IST
- MORE FROM WORLD
- Death of Libyan rebel leader stirs fears of tribal conflict
- US accuses Iran of 'secret deal' with al-Qaeda
- Scientist converts skin cells into brain cells
- South Africa urges circumcision to curb HIV
- US varsity with Indian students under scanner
- Decision making area inactive in schizophrenic brains
- New software quickly interprets brain cells
- 'Super antibody' fights off flu
- HIV patients 'eat dung to make drugs work' in Swaziland
- India to use UNSC presidency to establish credentials
GK NEWS NETWORK
Srinagar, July 29: Literally frustrated by the callous attitude of the state government over their demands, the college contractual lecturers Friday decided to go on fast unto death from Saturday.   More
- Srinagar City
Being stuck in a traffic jam is not everybodyís cup of tea. It becomes a nightmare and unbearable for people who are on a tight schedule and intending to beat deadlines. Almost every City has a big traffic More
GK NEWS NETWORK
Jammu, July 29: Now anyone caught feeding monkeys on Srinagar- Jammu Highway would have to pay a heavy fine, as the Wildlife department has decided to go tough against the practice. Officials said More
- South Asia
NISAR AHMED THOKAR
Islamabad, July 29: The Legislative Assembly of Pakistan administered Kashmir (PaK) on Friday elected the nominee of Pakistan Peoples Party (PPP) Sardar Muhammad Yaqoob Khan as regionís new president.& More
Benghazi, Libya, July 29: The top rebel military commander was killed Thursday, and members of his tribe greeted the announcement with gunfire and angry threats. The violent outburst stirred fears More