NONS may be game changer in Covid protection, doctors hope

‘Spray may be available in markets by year end’
NONS may be game changer in Covid protection, doctors hope
A Nitric Oxide Nasal Spray (NONS) is about to foray into the markets, including those in India, and many doctors are excited to see its efficacy.Special arrangement

Srinagar: Soon, people may be able to spray their noses with a virus-killing liquid, the same way sanitizers are sprayed on hands and surfaces to disinfect.

A Nitric Oxide Nasal Spray (NONS) is about to foray into the markets, including those in India, and many doctors are excited to see its efficacy.

Prof Parvaiz Koul ex-head department of Internal and Pulmonary Medicine at SKIMS Soura and Vice Chairman of Middle East, Eurasia and Africa Influenza Stakeholders Network (MENA ISN) on Thursday tweeted “Nitric oxide nasal spray may be the game changer in covid protection. Phase 3 trials underway. Preclinical data and phase 2 data very impressive. Kills more than 95% viruses (upto 99.9) in the respiratory tract in 2 minutes, conferring real protection. Waiting...”

While speaking to Greater Kashmir, he said that clinical trials of the spray were underway in many countries and till now, the drug had shown promise in eliminating the virus.

He said the most likely utility of the drug could be in settings where avoiding a crowd or an infected patient was not possible. “One could pop-up a couple of sprays and help in deactivation of the virus before it causes harm, in the upper respiratory tract only,” he said, adding that he has fingers crossed over the outcome of the drug in the clinical trials.

As per media reports, Glenmark Pharmaceuticals has partnered with SaNOtize to manufacture, market, and distribute NONS to India. The company got approval of Central Drugs Standard Control Organization (CDSCO) for phase three trials in August.

As per the company, NONS is safe and effective antiviral treatment to prevent the transmission of COVID-19, shorten its course, and reduce the severity of symptoms. Manufacturing companies claim it kills the COVID-19 virus in the upper airways, preventing it from incubating and spreading to the lungs. Nitric oxide has been proven to have anti-microbial properties and a direct effect on SARS-CoV-2.

Meanwhile, one Pharma company is working on inhalable Remdesivir.

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