Metabolic syndrome: A cluster of diseases

Metabolic syndrome is a type of opportunistic disease developing through disturbed physiological metabolism.
Metabolic syndrome: A cluster of diseases
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Metabolic syndrome is a type of opportunistic disease developing through disturbed physiological metabolism. It is a cluster of diseases comprising obesity, dyslipidemia, hypertension, and insulin resistance occurring in synergy. It increases one's risk of heart disease, stroke & diabetes. Its symptoms include development of obesity, increase in the waistline from outside, to glucose intolerance and hypertension from inside. It is widely prevalent in people who prefer sedentary mode of lifestyle and rely more on machines than putting sweat to carry out their day to day activities. People with insulin resistance, more precisely having glucose intolerance are more prone to develop this clustered disease. Metabolic syndrome, also called death quartet, or 'syndrome X', places an individual at risk for type 2 diabetes (T2D) and cardiovascular disease (CVD). it is becoming worldwide epidemic as a result of the increased prevalence of obesity and sedentary lifestyle, and it's prevalence in the adult population is relatively high. Often metabolic syndrome is mis-diagnosed and due to its complicated pathophysiology it's treatment is  improbable. Four elements comprising Metabolic syndrome have been identified as central obesity, also called as abdominal obesity with large waist line, dyslipoproteinemia (increased triglycerides and reduced high-density lipoprotein (HDL) cholesterol), hypertension and glucose intolerance (high fasting sugar level) and any person having at least three of these is likely to suffer from metabolic syndrome. The risk of having metabolic syndrome is closely linked to overweight and a larger lack of physical activity. In addition, Genetics (ethnicity and family history) and older age are other factors that play a role in development of metabolic syndrome. Other groups at increased risk for metabolic syndrome include, smooking, people who have a personal history of diabetes, Women who have a personal history of polycystic ovarian syndrome (a tendency to develop cysts in ovaries) and in general Women comparatively have more chances than men to develop metabolic syndrome. 

Metabolic syndrome is becoming more common due to rise in sedentary mode of lifestyle among adults. In the future, metabolic syndrome may overtake smoking as the leading risk factor for heart disease. It is possible to prevent or delay metabolic syndrome, mainly with lifestyle changes. A healthy lifestyle is a lifelong commitment. Successfully controlling metabolic syndrome requires long-term effort and teamwork with your health care providers. Heart-healthy lifestyle changes are the first line of treatment for metabolic syndrome. Lifestyle changes include healthy eating, maintaining a healthy weight, managing stress, physical activity, and quitting smoking. The major goal of treating metabolic syndrome is to reduce the risk of coronary heart disease and to delay the onset of type 2 diabetes, if it hasn't already developed. Long-term complications of diabetes often include heart and kidney disease, vision loss, and foot or leg amputation. 

People who are suffering from Metabolic syndrome need to increase their work activity. A routine long walk either in morning or evening will work best. The avoidance of high fatty foods including junk one's  and turning to green leafy vegetables is a necessary to build up good cholesterol and  provide space for body to lease out bad one.  More importantly, one must rely on his natural capacity & capability to carry out daily works than to depend on machines he himself developed for his goodwill but not to destroy his inner  potency and efficiency.

The Author is Medical Research fellow, working on Melanoma (Skin Cancer) at CSIR, Indian Institute of Integrative Medicine, Jammu (J&K).

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